What happens if you eat after taking sucralfate?

In this short article, we will answer the question “What happens if you eat after taking sucralfate?”, explain how to drug works and share eating tips for you to complement the treatment with sucralfate. 

What happens if you eat after taking sucralfate?

Sucralfate will not act as well when taken with food, and the ulcer will also not be well treated or healed. The most frequent consequence of stomach ulcers is internal bleeding. It might happen if an ulcer grows near a blood vessel. 

There are two types of bleeding that can occur: slow, chronic bleeding that results in anaemia and causes weariness, dyspnea, pale skin, and irregular heartbeat (palpitations). 

You must take sucralfate empty-handed for it to quickly assemble the compound that binds to the protein-rich exudate present on the surface of the ulcers. It prevents stomach acid from lysing blood clots by binding to albumin and fibrinogen. 

Sucralfate boosts the tissue quantities of fibroblast growth factors and epidermal growth factors when it is taken on an empty stomach. This results in higher in prostaglandins there at gastrointestinal tract lining, which helps to repair gastrointestinal ulcers. 

It’s also crucial to remember that sucralfate doesn’t absorb much through the mouth but stays in the gastrointestinal tract (GIT) for a long time. 

By hindering its absorption and lowering its oral bioavailability, the unabsorbed sucralfate can change the pharmacokinetics of the medications.

What are the indications and purposes of sucralfate?

The purpose of this drug is to treat chronic gastritis, duodenal ulcers, and stomach ulcers. Sucralfate’s polyanionic property gives it a cytoprotective effect. 

Sucralfate forms a gel that adheres to the stomach and duodenal mucosa by binding to positively charged proteins, offering uniform defence against acid assault, pepsin, and bile salts.

What conditions should not be used with sucralfate?

Patients who are hypersensitive to sucralfate or any other formulation ingredient should not use sucralfate. Pregnant women should not use this medication without consulting a doctor or a dentist.

How should I eat to complement the sucralfate treatment?

Because it can seriously harm health if not correctly managed, gastric ulcer is a serious digestive condition. In this way, watching what you eat is a crucial step in symptom relief. Following are some suggestions for managing this condition:

  1. Steer clear of powerful meals

Food significantly affects how stomach ulcer symptoms are attenuated or relieved. This is due to the disease’s effect on the stomach, which serves as the primary organ in the digesting process.

Therefore, avoiding foods that upset your stomach is a key piece of advice. Therefore, you must take the following things off your menu:

  • processed and yellow cheeses;
  • bacon, ham, sausage, and other processed meats;
  • processed and fried foods;
  • liver, chicken skin, and fatty red meats;
  • sugar in general and sweets;
  • prepared sauces and seasonings in cubes.
  1. Supplement your menu with probiotics and antioxidants

Examples of foods high in vitamin C and A include red fruits, flaxseed, papaya, and cucumber. These foods have antioxidant properties that have an anti-inflammatory effect on the body, reducing stomach ulcer symptoms.

Similar features also apply to probiotics, which are abundant in microbes that aid in the eradication of pathogenic bacteria and regulate bodily functions by reducing inflammation.

  1.  Steer clear of extended fasts

It is usual to experience that unpleasant stomach burning while going for extended durations without eating.  Due to the secretion of stomach acids and the organ’s lack of food, this happens.

Therefore, those who have gastritis or other types of stomach inflammation should steer clear of extended fasting and establish a three-hour feeding schedule. This mentality is sufficient to shield the stomach and prevent discomfort.

  1. Manage the intake of food

Large portions consumed at each meal are never healthy habits for anyone, but they are especially dangerous for individuals who have gastric ulcers. Extra food strains the digestive system more, resulting in pain and burning.

Manage the amount of food on the plate in this way. Not wanting to eat until you’re hungry is an excellent habit.  Additionally, you can fractionate meals, taking smaller meals more frequently throughout the day.

  1.  Select simple-to-digest foods.

Differentiating the diet of people with stomach ulcers is necessary. Choose foods that are simple to digest and low in fat to prevent overworking the stomach and the unpleasant sensations that can follow, such as:

  • fruits generally, except citrus fruits;
  • prepared vegetables
  • lean poultry, fish, and red meat;
  • natural whole yoghurt and skim milk.
  • whole-grain pasta, bread, and rice;
  • Decaf coffee;
  • blanched cheeses;
  • organic seasonings (fine herbs, garlic, onion, coriander and parsley).
  • Anyway, these are some pieces of advice that might help with the agony a gastrointestinal ulcer causes.
  • Seek the assistance of a specialist for the development of an adequate diet to prevent the deficit of some nutrients.


In this short article, we answered the question “What happens if you eat after taking sucralfate?”, explained how to drug works and shared eating tips for you to complement the treatment with sucralfate. 


Giesing DH, Bighley LD, Iles RL. Effect of food and antacid on binding of sucralfate to normal and ulcerated gastric and duodenal mucosa in rats. J Clin Gastroenterol. 1981;3(Suppl 2):111-6. PMID: 6895642.

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